Jeskai Ascendancy and Sorcerer Class on the battlefield.
Sorcerer Class is at least level two.
You control at least six creatures without summoning sickness.
Steps
Activate six creatures you control by tapping them, adding ({5} magic symbol) ({U} magic symbol) that can only be spent to cast instant and/or sorcery spells, or to gain a Class level.
Cast Whispers of the Muse with buyback by paying ({5} magic symbol) ({U} magic symbol) , triggering Jeskai Ascendancy's first and second abilities and Sorcerer Class's third ability if it is level three.
Resolve the Sorcerer Class trigger, if applicable, causing Whispers of the Muse to deal an amount of damage to each opponent equal to the number of instants and sorceries you've cast this turn.
Resolve the first Jeskai Ascendancy trigger, giving creatures you control +1/+1 until end of turn and untapping them.
Resolve the second Jeskai Ascendancy trigger, allowing you to loot.
Resolve Whispers of the Muse, causing you to draw a card and return Whispers of the Muse to your hand.
Repeat.
If you control seven or more creatures without summoning sickness, this combo nets near-infinite mana.
Results
Infinite draw triggers.
Near-infinite blue mana that can only be spent to cast instant and/or sorcery spells.
Near-infinite card draw.
Near-infinite damage.
Near-infinite looting.
Near-infinitely large creatures until end of turn.
Near-infinite magecraft triggers.
Near-infinite red mana that can only be spent to cast instant and/or sorcery spells.
Near-infinite self-discard triggers.
Near-infinite storm count.
Near-infinite untap of creatures you control.
Near-infinite mana creatures you control can produce.