Give Ashling the Pilgrim deathtouch by any method.
Activate Ashling the Pilgrim three times by paying {3}{R}{R}{R}, putting three +1/+1 counters on it, then removing all +1/+1 counters from it and dealing that much damage to each creature.
Each creature dealt damage by Ashling the Pilgrim dies due to Ashling the Pilgrim's deathtouch.
Scythe of the Wretched triggers for each creature that dies this way, returning them to the battlefield under your control, ensuring that Ashling the Piglrim is returned last so that Scythe of the Wretched will be attached to it.
You may repeat this combo as desired.

Gain control of all creatures without indestructible during each of your turns

Ashling the Pilgrim

Scythe of the Wretched

Activate Goblin Sharpshooter by tapping it, dealing 1 damage to target creature.
That creature dies from lethal damage due to Goblin Sharpshooter's deathtouch ability.
Goblin Sharpshooter triggers, untapping itself.
Repeat for each creature opponents control and whenever an opponent controls a creature.

Destroy all creatures opponents control

From now on, destroy any creatures opponents control at instant speed

Goblin Sharpshooter

Quietus Spike

Activate Triskelion's ability by removing a +1/+1 counter from it to deal 1 damage to itself.
Repeat step 1 an additional 2 times, killing Triskelion.
Scythe of the Wretched triggers, returning Triskelion to the battlefield with Scythe of the Wretched attached to it.
Repeat.

Infinite death triggers

Infinite ETB

Infinite LTB

Triskelion

Activate Kamahl by tapping it, dealing 3 damage to itself.
Kamahl dies, triggering Scythe of the Wretched, returning Kamahl to the battlefield from your graveyard, and attaching Scythe of the Wretched to it.
Repeat.

Kamahl, Pit Fighter

Deal combat damage to an opponent with the creature that has Quietus Spike attached.
Quietus Spike triggers, causing the opponent to lose half their life total, rounded up.
At the beginning of your end step, Wound Reflection triggers, causing the opponent to lose life equal to the life they lost this turn.
The opponent loses the game due to having zero or less life.

Near-infinite lifeloss for target opponent

Target opponent loses the game

Wound Reflection

Deal combat damage to an opponent using the creature that has Quietus Spike attached.
Quietus Spike triggers, causing the defending opponent to lose their entire life total due to Bloodletter of Aclazotz.
The opponent loses the game due to having 0 or less life.

Infinite lifeloss for target opponent

Bloodletter of Aclazotz

Deal combat damage to an opponent with the creature that has Quietus Spike attached.
Quietus Spike triggers, causing the opponent to lose half their life total, rounded up.
At the beginning of your end step, Astarion triggers, causing the opponent to lose life equal to the life they lost this turn.
The opponent loses the game due to having zero or less life.

Astarion, the Decadent

Deal combat damage to an opponent with the creature that has Quietus Spike attached.
Quietus Spike triggers, causing the opponent to lose half their life total, rounded up.
At the beginning of your end step, Warlock Class triggers, causing the opponent to lose life equal to the life they lost this turn.
The opponent loses the game due to having zero or less life.

Warlock Class

Deal combat damage to an opponent with the creature that has Quietus Spike attached.
Quietus Spike triggers, causing the opponent to lose half their life total, rounded up.
At the beginning of your end step, Archfiend of Despair triggers, causing the opponent to lose life equal to the life they lost this turn.
The opponent loses the game due to having zero or less life.

Archfiend of Despair

Deal combat damage to an opponent with the creature that has Quietus Spike attached.
Quietus Spike triggers, causing the opponent to lose half their life total, rounded up.
At the beginning of your end step, Blitzwing triggers, causing the opponent to lose life equal to the life they lost this turn.
The opponent loses the game due to having zero or less life.

Blitzwing, Cruel Tormentor // Blitzwing, Adaptive Assailant

Activate Deathbringer Thoctar by removing a +1/+1 counter from it, dealing 1 damage to any creature an opponent controls.
The creature dies as a state-based action due to Deathbringer Thoctar's deathtouch.
Deathbringer Thoctar triggers, putting a +1/+1 counter on itself.
Repeat as desired.
You may also repeat this combo whenever a creature enters the battlefield under an opponent's control.

Destroy any creature that enters the battlefield under an opponent's control

Deathbringer Thoctar

Give Pestilence Demon deathtouch by any method.
Activate Pestilence Demon by paying {B}, dealing 1 damage to each creature and player.
Each creature dealt damage by Pestilence Demon dies due to Pestilence Demon's deathtouch.
Scythe of the Wretched triggers for each creature that dies this way, returning them to the battlefield under your control, ensuring that Pestilence Demon is returned last so that Scythe of the Wretched will be attached to it.
You may repeat this combo as desired.

Pestilence Demon

Cast the instant or sorcery by paying its mana cost.
Holding priority, activate Stella Lee by tapping it, copying the instant or sorcery.
Resolve the copy of the instant or sorcery, untapping Stella Lee.
Repeat from step 2.

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