Cast a copy of Channel by paying {G}{G}.
Activate the ability granted by Channel by paying 1 life, adding {C}.
Repeat step 2 as desired.
Cast Jaya's Immolating Inferno by paying {R}{R} and all remaining available mana, dealing a large amount of damage to up to three targets.

Near-infinite damage

Yavimaya Bloomsage // Channel

Jaya's Immolating Inferno

Cast a copy of Channel by paying {G}{G}.
Activate the ability granted by Channel by paying 1 life, adding {C}.
Repeat step 2 as desired.
Cast Comet Storm by paying {R}{R} and all remaining available mana, dealing a large amount of damage to a set number of targets.

Comet Storm

Cast a copy of Channel by paying {G}{G}.
Activate the ability granted by Channel by paying 1 life, adding {C}.
Repeat step 2 as desired.
Cast Crackle with Power by paying {R}{R} and all remaining available mana, dealing a large amount of damage to a set number of targets.

Crackle with Power

Cast a copy of Channel by paying {G}{G}.
Activate the ability granted by Channel by paying 1 life, adding {C}.
Repeat step 2 as desired.
Cast Torment of Hailfire by paying {B}{B} and all remaining available mana. Each opponent will lose 3 life unless they sacrifice a nonland permanent or discard a card for each mana paid beyond the {B}{B}.

Near-infinite lifeloss

Torment of Hailfire

Cast a copy of Channel by paying {G}{G}.
Activate the ability granted by Channel by paying 1 life, adding {C}.
Repeat step 2 as desired.
Cast a copy of Exsanguinate by paying {B}{B} and all remaining available mana, causing each opponent to lose a significant amount of life and you to gain life equal to the life lost this way.

Near-infinite lifegain

Stensian Sanguinist // Exsanguinate

Cast a copy of Channel by paying {G}{G}.
Activate the ability granted by Channel by paying 1 life, adding {C}.
Repeat step 2 as desired.
Cast Exsanguinate by paying {B}{B} and all remaining available mana, causing each opponent to lose a significant amount of life and you to gain life equal to the life lost this way.

Exsanguinate

Cast a copy of Channel by paying {G}{G}.
Activate the ability granted by Channel by paying 1 life, adding {C}.
Repeat step 2 as desired.
Cast Debt to the Deathless by paying {W}{W}{B}{B} and all remaining available mana, causing each opponent to lose a significant amount of life and you to gain life equal to the life lost this way.

Debt to the Deathless

Cast a copy of Channel by paying {G}{G}.
Activate the ability granted by Channel by paying 1 life, adding {C}.
Repeat step 2 as desired.
Cast Ribbons from your graveyard by paying {B}{B} and all remaining available mana, causing each opponent to lose a significant amount of life.

Combos with "Yavimaya Bloomsage // Channel"