Cast Thud by paying {R} and sacrificing Serra Avatar, dealing damage equal to Serra Avatar's power to target opponent with a life total equal to or less than your life total.
The opponent loses the game due to having 0 or less life.

Near-infinite damage to one opponent

Target opponent loses the game

Thud

Serra Avatar

Cast Thud by paying {R} and sacrificing Soul of Eternity, dealing damage equal to Soul of Eternity's power to target opponent with a life total equal to or less than your life total.
The opponent loses the game due to having 0 or less life.

Soul of Eternity

Cast Body of Reaserch by paying {G}{G}{G}{U}{U}{U}, creating a 0/0 Fractal creature token with a number of +1/+1 counters equal to your library size.
Cast Thud by paying {R} and sacrificing the Fractal, dealing damage equal to the Fractal's power to an opponent.
The opponent loses the game due to having zero or less life.

Near-infinite damage

Body of Research

Cast Thud by paying {R} and sacrificing Angelic Enforcer, dealing damage equal to Angelic Enforcer's power to target opponent with a life total equal to or less than your life total.
The opponent loses the game due to having 0 or less life.

Enduring Angel // Angelic Enforcer

Cast Thud by paying {R} and sacrificing a creature you control with power seven or greater.
Holding priority, cast Reiterate with buyback by paying {4}{R}{R}, creating a copy of Thud and returning Reiterate to your hand.
Resolve the Thud copy, causing you to create at least seven 3/1 Elemental Shaman creature tokens with haste due to Hostility.
Activate Thermopod seven times by sacrificing seven Elemental Shamans, adding seven {R}.
Repeat from step 2 an arbitrarily large number of times.
Activate Thermopod's second ability by sacrificing Hostility, adding {R}.
Hostility dies, shuffling itself into your library from your graveyard.
Cast Reiterate with buyback by paying {4}{R}{R}, creating a copy of Thud and returning Reiterate to your hand.
Resolve the Thud copy, dealing at least seven damage to any target.
Repeat from step 8.

Infinite creature tokens with haste

Infinite damage

Infinite death triggers

Infinite creature ETB

Infinite creature LTB

Infinite magecraft triggers

Infinite red mana

Infinite creature sacrifice triggers

Infinite storm count

Hostility

Reiterate

Thermopod

Cast Thud by paying {R} and sacrificing a creature you control with power seven or greater.
Holding priority, cast Reiterate with buyback by paying {4}{R}{R}, creating a copy of Thud and returning Reiterate to your hand.
Resolve the Thud copy, causing you to create at least seven 3/1 Elemental Shaman creature tokens with haste due to Hostility.
Activate Phyrexian Altar seven times by sacrificing seven Elemental Shamans, adding {5}{R}{R}.
Repeat from step 2 an arbitrarily large number of times.
Activate Phyrexian Altar by sacrificing Hostility, adding {R}.
Hostility dies, shuffling itself into your library from your graveyard.
Cast Reiterate with buyback by paying {4}{R}{R}, creating a copy of Thud and returning Reiterate to your hand.
Resolve the Thud copy, dealing at least seven damage to any target.
Repeat from step 8.

Combos with "Thud"