Cast Beacon of Immortality by paying {5}{W}, causing target opponent to lose life equal to their life total due to Tainted Remedy.
The opponent loses the game due to having zero or less life.

Target opponent loses the game

Beacon of Immortality

Tainted Remedy

Activate Marvin using Grove of the Burnwillows' second ability by tapping it, adding {R} or {G} and causing each opponent to lose 1 life due to Tainted Remedy.
Activate Marvin using Pili-Pala's ability by paying {2} and untapping it, adding {1}.
Repeat.

Infinite lifeloss

Grove of the Burnwillows

Pili-Pala

Marvin, Murderous Mimic

Nature's Revolt

Cast Angel's Grace by paying {W}, causing you to be unable to lose the game this turn.
Cast Volcano Hellion by paying {2}{R}{R}.
Volcano Hellion enters the battlefield, dealing an arbitrarily large amount of damage to Grollub and reduing your lifetotal to one due to Angel's Grace.
Grollub triggers, causing each opponent to lose life equal to the damage dealt to it due to Tainted Remedy.
Each opponent loses the game due to having zero or less life.

Each opponent loses the game

Grollub

Volcano Hellion

Angel's Grace

Cast Volcano Hellion by paying {2}{R}{R}.
Volcano Hellion enters the battlefield, dealing an arbitrarily large amount of damage to you and Grollub.
Grollub triggers, causing each opponent to lose life equal to the damage dealt to it due to Tainted Remedy.
Each opponent loses the game due to having zero or less life.

Platinum Emperion

Cast Magister Sphinx by paying {4}{W}{U}{B}.
Magister Sphinx enters the battlefield, causing target opponent's life total to become ten.
Cast Aria of Flame by paying {2}{R}.
Aria of Flame enters the battlefield, causing each opponent to lose ten life.
The opponent whose life total was set in step 2 loses the game due to having zero or less life.

Magister Sphinx

Aria of Flame

Platinum Angel

Cast Revenge by paying {4}{W}{B}.
Hive Mind triggers, causing each opponent to copy Revenge.
Resolve the first opponent's copy of Revenge, causing the opponent to lose life equal to their life total, and causing a different player to lose half their life total, rounded up.
The opponent loses the game due to having zero life.
Repeat from step 3 for each remaining opponent's copy of Revenge.

Combos with "Tainted Remedy"