Activate all mana producing lands you control besides Sanctum of Eternity by tapping them, adding at least {9}{R}{G}{W}.
Activate Sanctum of Eternity by paying {2} and tapping it, returning Zacama from the battlefield to your hand.
Cast Zacama by paying {6}{R}{G}{W}.
Zacama triggers, untapping all lands you control.
Repeat.

Destroy all artifacts and enchantments opponents control

Infinite damage to creatures

Infinite enchantment destruction

Infinite creature ETB

Infinite lifegain

Infinite lifegain triggers

Infinite creature LTB

Infinite mana lands you control can produce

Infinite storm count

Zacama, Primal Calamity

Sanctum of Eternity

Activate Estrid's second loyalty ability by removing one loyalty counter, creating a Mask Aura token and attaching it to Sanctum of Eternity.
Activate Sanctum of Eternity by paying {2} and tapping it, returning Estrid to your hand.
Activate all other enchanted permanents that can produce at least {4}{W}{U}{G}.
Cast Estrid by paying {1}{W}{U}{G}.
Activate Estrid's first loyalty ability by putting two loyalty counters on it, untapping all enchanted permanents you control.

Infinite colored mana

Infinite colorless mana

Infinite mana enchanted permanents you control can produce

Estrid, the Masked

Activate any number of lands by tapping them, adding at least {12}
Cast Emrakul by paying {10} plus commander tax if applicable.
Emrakul triggers, untapping all lands you control.
Resolve Emrakul. Then, activate Sanctum of Eternity's second ability by paying {2} and tapping it, returning Emrakul from the battlefield to your hand.
Repeat.

Infinite untap of lands you control

Emrakul, the Exigent Doom

Cast Time Warp by paying {3}{U}{U}, granting you an extra turn after this one and exiling it due to rebound.
At the beginning of your next upkeep, rebound triggers, causing you to cast the exiled spell without paying its mana cost.
Activate Sanctum of Eternity by tapping it and paying {2}, returning Venser from the battlefield to your hand.
Cast Venser by paying {2}{U}{U}, returning the extra turn spell to your hand.
Repeat each turn.

Infinite turns

Lock

Cast Through Time

Venser, Shaper Savant

Time Warp

Cast Temporal Manipulation by paying {3}{U}{U}, granting you an extra turn after this one and exiling it due to rebound.
At the beginning of your next upkeep, rebound triggers, causing you to cast the exiled spell without paying its mana cost.
Activate Sanctum of Eternity by tapping it and paying {2}, returning Venser from the battlefield to your hand.
Cast Venser by paying {2}{U}{U}.
When Venser enters the battlefield, they trigger, returning the extra turn spell to your hand.
Repeat each turn.

Temporal Manipulation

Cast Capture of Jingzhou by paying {3}{U}{U}, granting you an extra turn after this one and exiling it due to rebound.
At the beginning of your next upkeep, rebound triggers, causing you to cast the exiled spell without paying its mana cost.
Activate Sanctum of Eternity by tapping it and paying {2}, returning Venser from the battlefield to your hand.
Cast Venser by paying {2}{U}{U}.
When Venser enters the battlefield, they trigger, returning the extra turn spell to your hand.
Repeat each turn.

Capture of Jingzhou

Cast Nexus of Fate by paying {5}{U}{U}, granting you an extra turn after this one and exiling it due to rebound.
At the beginning of your next upkeep, rebound triggers, causing you to cast the exiled spell without paying its mana cost.
Activate Sanctum of Eternity by tapping it and paying {2}, returning Venser from the battlefield to your hand.
Cast Venser by paying {2}{U}{U}.
When Venser enters the battlefield, they trigger, returning the extra turn spell to your hand.
Repeat each turn.

Nexus of Fate

Cast Walk the Aeons by paying {4}{U}{U}, granting you an extra turn after this one and exiling it due to rebound.
At the beginning of your next upkeep, rebound triggers, causing you to cast the exiled spell without paying its mana cost.
Activate Sanctum of Eternity by tapping it and paying {2}, returning Venser from the battlefield to your hand.
Cast Venser by paying {2}{U}{U}.
When Venser enters the battlefield, they trigger, returning the extra turn spell to your hand.
Repeat each turn.

Combos with "Sanctum of Eternity"