Cast Magister Sphinx by paying {4}{W}{U}{B}.
When Magister Sphinx enters the battlefield, it triggers, causing an opponent's life total to become 10.
Deal combat damage to that opponent using Ezio.
Ezio triggers, causing you to pay {W}{U}{B}{R}{G} to have that opponent lose the game.

Near-infinite lifeloss for target opponent

Target opponent loses the game

Ezio Auditore da Firenze

Magister Sphinx

Cast Magister Sphinx by paying {4}{W}{U}{B}.
When Magister Sphinx enters the battlefield, it triggers, causing an opponent with at least twenty life to lose life until their life total is equal to ten.
At the beginning of your end step, Wound Reflection triggers, causing each opponent to lose life equal to the life they lost this turn.
The opponent targeted by Magister Sphinx in step 1 loses the game due to having zero or less life.

Wound Reflection

Cast Magister Sphinx by paying {4}{W}{U}{B}.
When Magister Sphinx enters the battlefield, it triggers, causing an opponent with at least twenty life to lose life until their life total is equal to ten.
At the beginning of your end step, Archfiend of Despair triggers, causing each opponent to lose life equal to the life they lost this turn.
The opponent targeted by Magister Sphinx in step 1 loses the game due to having zero or less life.

Archfiend of Despair

Cast Magister Sphinx targetinging an opponent, putting their life total to 10.
Cast Hidetsugu's Second Rite targeting them, dealing 10 damage to them.

Target player loses the game

Hidetsugu's Second Rite

Cast Magister Sphinx by paying {4}{W}{U}{B}.
When Magister Sphinx enters the battlefield, it triggers, causing an opponent with at least twenty life to lose life until their life total is equal to ten.
At the beginning of your end step, Warlock Class triggers, causing each opponent to lose life equal to the life they lost this turn.
The opponent targeted by Magister Sphinx in step 1 loses the game due to having zero or less life.

Warlock Class

Cast Magister Sphinx by paying {4}{W}{U}{B}.
Magister Sphinx enters the battlefield, causing target opponent's life total to become 10.
Cast Aria of Flame by paying {2}{R}.
Aria of Flame enters the battlefield, causing each opponent to lose 10 life due to Plague Drone.
The opponent who was targeted in step 2 loses the game due to having zero life.

Infinite lifeloss for target opponent

Aria of Flame

Plague Drone

Cast Magister Sphinx by paying {4}{W}{U}{B}.
Magister Sphinx enters the battlefield, causing target opponent's life total to become ten.
Cast Aria of Flame by paying {2}{R}.
Aria of Flame enters the battlefield, causing each opponent to lose ten life.
The opponent whose life total was set in step 2 loses the game due to having zero or less life.

Combos with "Magister Sphinx"