Cast Glorious End from your graveyard by paying {2}{R}, causing it to gain demonstrate due to The Twelfth Doctor.
Glorious End's demonstrate ability triggers, causing you and an opponent to copy it.
Resolve the opponent's copy of Glorious End, ending the turn, thus exiling all other spells and abilities on the stack.
The opponent will then lose the game during their next end step due to Glorious End's triggered ability.

Target opponent loses the game at the beginning of their next end step

Kess, Dissident Mage

The Twelfth Doctor

Glorious End

Cast Walk the Aeons either from your hand or from your graveyard with buyback by paying {4}{U}{U} and sacrificing three Islands, causing you to take an extra turn after this one and returning Walk the Aeons to your hand.
Play an Island from your graveyard.
Move to your next turn.
Cast Walk the Aeons by paying {4}{U}{U}, causing you to take an extra turn after this one.
Play two Islands from your graveyard.
Move to your next turn.
Repeat.

Infinite turns

Lock

Walk the Aeons

Crucible of Worlds

Ghirapur Orrery

Cast Rise of the Eldrazi either from your hand or from your graveyard by paying {9}{C}{C}{C}, causing target player to draw four cards, and you to destroy target permanent, take an extra turn after this one and exile Rise of the Eldrazi.
Move to your next turn.
Activate Isochron Scepter by paying {2} and tapping it, casting a copy of Pull from Eternity without paying its mana cost.
Resolve the Pull from Eternity copy, putting Rise of the Eldrazi into your graveyard from exile.
Repeat.

Isochron Scepter

Pull from Eternity

Rise of the Eldrazi

Cast Expropriate by paying {7}{U}{U}, causing you to take at least one extra turn after this one and exile Expropriate.
Activate Isochron Scepter by paying {2} and tapping it, casting a copy of Pull from Eternity without paying its mana cost.
Resolve Pull from Eternity, putting Expropriate into your graveyard from exile.
Move to your next turn.
Cast Expropriate from your graveyard by paying {7}{U}{U}, causing you to take an extra turn after this one and exile Expropriate.
Repeat from step 2.

Expropriate

Cast Temporal Mastery by paying {5}{U}{U}, causing you to take an extra turn after this one and exile Temporal Mastery.
Activate Isochron Scepter by paying {2} and tapping it, casting a copy of Pull from Eternity without paying its mana cost.
Resolve Pull from Eternity, putting Temporal Mastery into your graveyard from exile.
Move to your next turn.
Cast Temporal Mastery from your graveyard by paying {5}{U}{U}, causing you to take an extra turn after this one and exile Temporal Mastery.
Repeat from step 2.

Temporal Mastery

Cast Part the Waterveil by paying {4}{U}{U}, causing you to take an extra turn after this one and exile Part the Waterveil.
Activate Isochron Scepter by paying {2} and tapping it, casting a copy of Pull from Eternity without paying its mana cost.
Resolve Pull from Eternity, putting Part the Waterveil into your graveyard from exile.
Move to your next turn.
Cast Part the Waterveil from your graveyard by paying {4}{U}{U}, causing you to take an extra turn after this one and exile Part the Waterveil.
Repeat from step 2.

Part the Waterveil

Cast Temporal Trespass by paying {8}{U}{U}{U}, causing you to take an extra turn after this one and exile Temporal Trespass.
Activate Isochron Scepter by paying {2} and tapping it, casting a copy of Pull from Eternity without paying its mana cost.
Resolve Pull from Eternity, putting Temporal Trespass into your graveyard from exile.
Move to your next turn.
Cast Temporal Trespass from your graveyard by paying {8}{U}{U}{U}, causing you to take an extra turn after this one and exile Temporal Trespass.
Repeat from step 2.

Temporal Trespass

Cast Karn's Temporal Sundering by paying {4}{U}{U}, causing you to take an extra turn after this one and exile Karn's Temporal Sundering.
Activate Isochron Scepter by paying {2} and tapping it, casting a copy of Pull from Eternity without paying its mana cost.
Resolve Pull from Eternity, putting Karn's Temporal Sundering into your graveyard from exile.
Move to your next turn.
Cast Karn's Temporal Sundering from your graveyard by paying {4}{U}{U}, causing you to take an extra turn after this one and exile Karn's Temporal Sundering.
Repeat from step 2.

Combos with "Kess, Dissident Mage"