Give Boros Reckoner lifelink.
Deal damage to Boros Reckoner.
Boros Reckoner triggers, dealing that much damage to itself and causing you to gain that much life.
Repeat step 4 any number of times.

Infinite lifegain

Infinite lifegain triggers

Boros Reckoner

Indestructibility

Deal damage to Spitemare.
Spitemare triggers, dealing double that damage to itself.
Repeat step 2 an arbitrarily large amount of times.
Spitemare triggers, dealing an arbitrarily large amount of damage to any target.

Infinite damage to one opponent

Furnace of Rath

Spitemare

Whenever a creature enters the battlefield, Lethal Vapors triggers, destroying that creature.
Activating Lethal Vapors' ability will not destroy it due to it being indestructible.

Destroy all creatures that enter the battlefield

Lock

Lethal Vapors

Cast Worms of the Earth.
Cast Indestructibility enchanting Worms of the Earth.
Player's can not play lands or have lands enter the battlefield, and paying the cost to remove Worms of the Earth does not destroy it due to Indestructibility

Combos with "Indestructibility"