Activate Skirge Familiar by discarding Golgari Brownscale, adding {B}.
Activate Greed by paying {B} and 2 life, causing you to mill two cards and return Golgari Brownscale from your graveyard to your hand.
Golgari Brownscale triggers, causing you to gain 2 life.
Repeat.

Infinite self-mill

Near-infinite lifegain triggers

Near-infinite self-discard triggers

Golgari Brownscale

Greed

Skirge Familiar

Activate Golgari Brownscale's cycling ability by paying {0} and discarding it, causing you to mill a number of cards and return Golgari Brownscale from your graveyard to your hand due to its dredge ability.
Repeat.

Rhet-Tomb Mystic

New Perspectives

Put a +1/+1 counter on Benthic Biomancer.
Benthic Biomancer triggers, causing you to mill two cards and return Golgari Brownscale from your graveyard to your hand, and then causing you to discard Golgari Brownscale.
Thran Vigil triggers, putting a +1/+1 counter on Benthic Biomancer.
Repeat from step 2.

Thran Vigil

Benthic Biomancer

Activate a permanent by tapping it, adding at least {B}.
Activate Mind Over Matter by discarding Golgari Brownscale, untapping the mana-producing permanent.
Activate Greed by paying {B} and 2 life, causing you to mill two cards and return Golgari Brownscale from your graveyard to your hand.
Golgari Brownscale triggers, causing you to gain 2 life.
Repeat.

Combos with "Golgari Brownscale"