Gain life.
Defiant Bloodlord triggers, causing an opponent to lose 1 life.
Exquisite Blood triggers, causing you to gain 1 life.
Repeat from step 2.

Infinite lifegain triggers

Infinite lifeloss

Infinite lifegain

Defiant Bloodlord

Exquisite Blood

Declare Angelic Enforcer as an attacker.
Angelic Enforcer triggers, doubling your life total.
Defiant Bloodlord triggers, causing target opponent whose life total is less than or equal to Angelic Enforcer's power to lose life equal to the life you gained.
That opponent loses the game due to having 0 or less life.

Near-infinite lifegain

Near-infinite lifeloss for target opponent

Enduring Angel // Angelic Enforcer

Activate Disciple of Griselbrand by paying {1} and sacrificing Serra Avatar, causing you to gain life equal to Serra Avatar's toughness.
Defiant Bloodlord triggers, causing target opponent to lose life equal to the life you gained.

Disciple of Griselbrand

Serra Avatar

At the beginning of your upkeep, Doomgape triggers, causing you to sacrifice Serra Avatar and gain life equal to its toughness.
Defiant Bloodlord triggers, causing an opponent to lose life equal to the life you gained.

Doomgape

At the beginning of your upkeep, Doomgape triggers, causing you to sacrifice Soul of Eternity and gain life equal to its toughness.
Defiant Bloodlord triggers, causing an opponent to lose life equal to the life you gained.

Soul of Eternity

Cast Volcano Hellion by paying {2}{R}{R}.
When Volcano Hellion enters the battlefield, it triggers, dealing an arbitrarily large amount of damage to you and Volcano Hellion.
Instead of you losing the game as a state-based action, Lich's Mirror causes you to shuffle your hand, graveyard and all permanents you own into your library, causing Defiant Bloodlord to phase in as Oubliette leaves the battlefield, and setting your life total to 20.
Defiant Bloodlord triggers, causing an opponent to lose life equal to the life you gained.

Infinite lifeloss for target opponent

Volcano Hellion

Lich's Mirror

Oubliette

Cast Volcano Hellion by paying {2}{R}{R}.
When Volcano Hellion enters the battlefield, it triggers, dealing an arbitrarily large amount of damage to you and Volcano Hellion.
Instead of you losing the game as a state-based action, Lich's Mirror causes you to shuffle your hand, graveyard and all permanents you own into your library, causing Defiant Bloodlord to phase in as The Moment leaves the battlefield, and setting your life total to 20.
Defiant Bloodlord triggers, causing an opponent to lose life equal to the life you gained.

Combos with "Defiant Bloodlord"