Activate Ashnod's Altar by sacrificing the creature with persist.
When that creature dies, its persist ability triggers, returning it from your graveyard to the battlefield without a -1/-1 counter on it due to Darksteel Angel
Repeat.

Infinite colorless mana

Infinite creature ETB

Infinite creature LTB

Infinite creature sacrifice triggers

Infinite death triggers

Persist Creature

Ashnod's Altar

Darksteel Angel

Activate Wall of Blood by paying life.
Repeat step 1 until you have 0 life.
Cast Mister Negative by paying {5}{W}{B} plus commander tax if applicable.
When Mister Negative enters, it triggers, swapping your life total with an opponent's.
The opponent loses the game due to having 0 life.

Near-infinite lifeloss for target opponent

Target opponent loses the game

Mister Negative

Wall of Blood

Cast Transcendence by paying {3}{W}{W}{W}.
Transcendence triggers due to you having 20 or more life. However, you cannot lose the game due to Darksteel Angel.
Step 2 repeats in an infinite loop, causing the game to end in a draw if it isn't interacted with.

Draw the game

Transcendence

Activate Ashnod's Altar by sacrificing Darksteel Angel
When Darksteel Angel dies, its persist ability triggers, returning it from your graveyard to the battlefield without a -1/-1 counter on it due to its static effect.
Repeat.

Eirdu, Carrier of Dawn // Isilu, Carrier of Twilight

Draw a card.
Niv-Mizzet triggers, dealing 1 damage to you.
Vilis triggers, causing you to draw a card.
Repeat from step 2 until your library is empty, preventing a game loss with Darksteel Angel.

Infinite card draw

Infinite draw triggers

Vilis, Broker of Blood

Niv-Mizzet, Parun

Cast Volcano Hellion by paying {2}{R}{R}.
When Volcano Hellion enters, it triggers, dealing an arbitrarily large amount of damage to Smaug and you. You cannot lose the game due to Darksteel Angel
Smaug triggers, creating an amount of Treasure tokens equal to the damage it was dealt.

Infinite Treasure tokens

Infinite colored mana

Infinite artifact ETB

Infinite artifact LTB

Infinite artifact sacrifice triggers

Infinite artifact tokens

Smaug the Impenetrable

Volcano Hellion

Activate Frenetic Efreet an arbitrarily large number of times by paying {0}.
Resolve a Frenetic Efreet ability, causing you to flip a coin.
Karplusan Minotaur triggers. If you won the flip, it deals 1 damage to any target you choose. If you lost the flip, it deals 1 damage to a target of an opponent's choosing. You cannot lose the game due to this damage due to Darksteel Angel, and Karplusan Minotaur cannot be destroyed due to its indestructibility or protection.
Repeat from step 2.

Combos with "Darksteel Angel"