Activate Vilis by paying {B} and 2 life, targeting any creature.
Vilis triggers, causing you to draw two cards.
Curse of Fool's Wisdom triggers twice.
Resolve a Curse of Fool's Wisdom trigger, causing you to gain 2 life and lose 2 life.
Repeat from step 2.

Infinite card draw

Infinite draw triggers

Near-infinite lifegain triggers

Vilis, Broker of Blood

Curse of Fool's Wisdom

Draw a card.
Curse of Fool's Wisdom triggers, causing you to lose 2 life and gain 2 life.
Drogskol Reaver triggers, causing you to draw a card.
Repeat from step 2 until your library is empty.
Respond to the final Curse of Fool's Widsom trigger by removing a combo piece or winning the game to avoid losing due to drawing from an empty library.

Combos with "Curse of Fool's Wisdom"