Activate Prognostic Sphinx by discarding a card.
Curator of Mysteries triggers, causing you to draw a card due to Eligeth.
Resolve the Prognostic Sphinx ability.
Repeat.

Infinite draw triggers

Infinite rummaging

Infinite self-discard triggers

Eligeth, Crossroads Augur

Curator of Mysteries

Prognostic Sphinx

During your cleanup step, discard to your maximum hand size.
When you discard a card, Curator of Mysteries triggers, causing you to draw a card due to Eligeth.
Pass priority, moving to an additional cleanup step.
Repeat until there are no cards left in your library.
Laboratory Maniac's effect causes you to win the game.

Infinite looting

Win the game

Laboratory Maniac

During your cleanup step, discard to your maximum hand size.
When you discard a card, Curator of Mysteries triggers, causing you to draw a card due to Eligeth.
Pass priority, moving to an additional cleanup step.
Repeat until there are no cards left in your library.
Jace's effect causes you to win the game.

Jace, Wielder of Mysteries

Activate Mind Over Matter by discarding a card.
Curator of Mysteries triggers, causing you to scry 1.
Matoya triggers, causing you to draw a card.
Resolve the Mind Over Matter ability.
Repeat.

Near-infinite untap of permanents you control

Near-infinite mana permanents you control can produce

Matoya, Archon Elder

Mind Over Matter

When an opponent controls an untapped creature, activate a mana-producing permanent by tapping it, adding at least {1}.
Activate Mind Over Matter by discarding a card, targeting the mana-producing permanent.
Curator of Mysteries triggers, causing you to scry 1.
Elvish Mariner triggers, causing you to tap an untapped creature an opponent controls.
Hylda of the Icy Crown triggers, causing you to pay {1} to scry 2 and draw a card.
Elvish Mariner triggers, causing you to tap nothing.
Resolve the Mind Over Matter ability from step 2, untapping the permanent.
Repeat as desired.

Tap all creatures opponents control during each turn

Hylda of the Icy Crown

Elvish Mariner

When an opponent controls an untapped creature, activate Skirge Familiar by discarding a card, adding {B}.
Curator of Mysteries triggers, causing you to scry 1.
Elvish Mariner triggers, causing you to tap an untapped creature an opponent controls.
Hylda of the Icy Crown triggers, causing you to pay {1} to scry 2 and draw a card.
Elvish Mariner triggers, causing you to tap nothing.
Repeat as desired.

Combos with "Curator of Mysteries"