Activate Lotus Petal by tapping and sacrificing it, adding {U}.
Cast Lotus Petal from your graveyard for its escape cost by exiling three cards besides Brain Freeze from your graveyard.
Repeat from step 1 one additional time.
Cast Brain Freeze either from your hand by paying {1}{U}, or from your graveyard for its escape cost by paying {1}{U} and exiling three cards from your graveyard.
Brain Freeze's storm ability triggers, creating at least two copies of Brain Freeze targeting yourself, and any remaining copies targeting an opponent.
Resolve each Brain Freeze, causing yourself to mill nine cards and, if applicable, an opponent to mill three cards for each Brain Freeze remaining.
Repeat.

Infinite self-mill

Near-infinite magecraft triggers

Near-infinite mill

Underworld Breach

Lotus Petal

Brain Freeze

Activate Lion's Eye Diamond by discarding your hand and sacrificing it, adding {U}{U}{U}.
Cast Lion's Eye Diamond from your graveyard for its escape cost by exiling three cards besides Brain Freeze from your graveyard.
Cast Brain Freeze from your graveyard for its escape cost by paying {1}{U} and exiling three cards from your graveyard.
Brain Freeze's storm ability triggers, creating at least one copy of Brain Freeze targeting yourself, and any remaining copies targeting an opponent.
Resolve each Brain Freeze, causing yourself to mill six cards and, if applicable, an opponent to mill three cards for each Brain Freeze remaining.
Repeat.

Near-infinite colored mana

Near-infinite storm count

Lion's Eye Diamond

Cast High Tide by paying {U}.
Activate up to three Islands by tapping them, adding {U}{U}{U}.
High Tide triggers three times, adding {U}{U}{U}.
Cast Brain Freeze for its escape cost by paying {1}{U} and exiling three other cards from your graveyard.
Brain Freeze's storm ability triggers, copying Brain Freeze for each spell you've cast before it this turn, with one copy targeting you and all remaining copies targeting any player(s).
Resolve all Brain Freezes, causing you to mill six cards, and each player to mill three cards for each Brain Freeze that targeted them.
Cast Frantic Search for its escape cost by paying {2}{U} and exiling three other cards from your graveyard, causing you to loot twice and untap three Islands.
Repeat.
Once you have milled your entire library, you may use the remaining {U} to cast Brain Freeze repeatedly targeting your opponents.

Near-infinite blue mana

Near-infinite draw triggers

Near-infinite looting

Near-infinite self-discard triggers

Near-infinite self-mill

Frantic Search

High Tide

Activate Lotus Petal by sacrificing it, adding {U}.
Cast Brain Freeze by paying {U}, targeting yourself.
If you have less than two experience counters, Mizzix triggers, causing you to get an experience counter.
Brain Freeze's storm ability triggers, creating a copy of Brain Freeze for each other spell you've cast this turn, with one copy targeting yourself and all remaining copies targeting any player.
Resolve all Brain Freeze spells, causing yourself to mill six cards and all other targeted players to mill three cards for each Brain Freeze.
Cast Lotus Petal from your graveyard for its escape cost by paying {0} and exiling three cards from your graveyard.
Activate Lotus Petal by sacrificing it, adding {U}.
Cast Brain Freeze from your graveyard for its escape cost by paying {U} and exiling three cards from your graveyard, targeting yourself.
Repeat from step 4.

Mizzix of the Izmagnus

Activate Lotus Petal by tapping it and sacrificing it, adding {U}.
Activate Emry by tapping it, allowing you to cast Lotus Petal from your graveyard this turn.
Activate Freed from the Real by paying {U}, untapping Emry.
Cast Lotus Petal from your graveyard by paying {0}.
Repeat an arbitrarily large number of times.
Cast Brain Freeze.
Brain Freeze's storm ability triggers, copying it for each spell cast before it this turn.
Resolve the all the Brain Freeze copies and Brain Freeze, milling any number of players for an arbitrarily large amount.

Infinite artifact ETB

Infinite artifact LTB

Infinite artifact sacrifice triggers

Infinite magecraft triggers

Infinite mill

Infinite storm count

Infinite creature LTB

Infinite creature ETB

Emry, Lurker of the Loch

Freed from the Real

Cast Mind's Desire for {4}{U}{U}.
Eye of the Storm and Mind's Desire each trigger.
Resolve the Mind's Desire trigger, copying it zero times.
Resolve the Eye of the Storm trigger, exiling Mind's Desire, copying Mind's Desire and Saheeli's Artistry, and casting the Mind's Desire copy then the Saheeli's Artistry copy, targeting Mirror of Fate, without paying their mana costs.
The Mind's Desire copy triggers, creating an additional Mind's Desire copy for each spell cast before it this turn.
Resolve those copies, exiling random cards from your library that you may play this turn.
Resolve the Saheeli's Artistry copy, creating a token copy of Mirror of Fate.
Activate any Mirror of Fate by tapping and sacrificing it, exiling all cards from your library and putting Saheeli's Artistry from exile on top of your library.
Resolve the remaining Mind's Desire copy, exiling Saheeli's Artistry from your library and allowing you to cast it this turn.
Cast Saheeli's Artistry from exile without paying its mana cost, choosing any target.
Eye of the Storm triggers, exiling Saheeli's Artistry, copying Mind's Desire and Saheeli's Artistry, and casting the Mind's Desire copy then the Saheeli's Artistry copy, targeting Mirror of Fate, without paying their mana costs.
The Mind's Desire copy triggers, creating an additional Mind's Desire copy for each spell cast before it this turn.
Resolve these copies, failing to exile anything from your empty library.
Resolve the Saheeli's Artistry copy, creating a token copy of Mirror of Fate.
Repeat from step 8.
Once you have infinite storm count, repeat the loop but put Brain Freeze on top of your library with a Mirror of Fate activation in step 8.
Once Mind's Desire has exiled Brain Freeze, cast Brain Freeze from exile without paying its mana cost.
Brain Freeze and Eye of the Strom each trigger.
Resolve Brain Freeze's trigger, creating any number of copies of itself targeting any number of players.

Infinite creature tokens

Eye of the Storm

Mind's Desire

Mirror of Fate

Saheeli's Artistry

Cast Mind's Desire for {4}{U}{U}.
Eye of the Storm and Mind's Desire each trigger.
Resolve the Mind's Desire trigger, copying it zero times.
Resolve the Eye of the Storm trigger, exiling Mind's Desire, copying Mind's Desire and Stolen Identity, and casting the Mind's Desire copy then the Stolen Identity copy, targeting Mirror of Fate, without paying their mana costs.
The Mind's Desire copy triggers, creating an additional Mind's Desire copy for each spell cast before it this turn.
Resolve those copies, exiling random cards from your library that you may play this turn.
Resolve the Stolen Identity copy, creating a token copy of Mirror of Fate.
Activate any Mirror of Fate by tapping and sacrificing it, exiling all cards from your library and putting Stolen Identity from exile on top of your library.
Resolve the remaining Mind's Desire copy, exiling Stolen Identity from your library and allowing you to cast it this turn.
Cast Stolen Identity from exile without paying its mana cost, choosing any target.
Eye of the Storm triggers, exiling Stolen Identity, copying Mind's Desire and Stolen Identity, and casting the Mind's Desire copy then the Stolen Identity copy, targeting Mirror of Fate, without paying their mana costs.
The Mind's Desire copy triggers, creating an additional Mind's Desire copy for each spell cast before it this turn.
Resolve these copies, failing to exile anything from your empty library.
Resolve the Stolen Identity copy, creating a token copy of Mirror of Fate.
Repeat from step 8.
Once you have infinite storm count, repeat the loop but put Brain Freeze on top of your library with a Mirror of Fate activation in step 8.
Once Mind's Desire has exiled Brain Freeze, cast Brain Freeze from exile without paying its mana cost.
Brain Freeze and Eye of the Strom each trigger.
Resolve Brain Freeze's trigger, creating any number of copies of itself targeting any number of players.

Stolen Identity

Combos with "Brain Freeze"