Cast Fate Trasnfer by paying {1}{U/B}, moving all counters from Eternity Vessel onto Dragonspark Reactor.
Activate Dragonspark Reactor by paying {4} and sacrificing it, dealing damage equal to the number of charge counters on it to an opponent and up to one target creature.
The opponent loses the game due to having 0 or less life.

Near-infinite damage to one opponent

Target opponent loses the game

Eternity Vessel

Dragonspark Reactor

Fate Transfer

March of the Machines

Activate Karn twice by paying {2}, causing Eternity Vessel and Dragonspark Reactor to become artifact creatures until end of turn.
Cast Fate Trasnfer by paying {1}{U/B}, moving all counters from Eternity Vessel onto Dragonspark Reactor.
Activate Dragonspark Reactor by paying {4} and sacrificing it, dealing damage equal to the number of charge counters on it to an opponent and up to one target creature.
The opponent loses the game due to having 0 or less life.

Karn, Silver Golem

Declare Genestealer Patriarch as an attacker.
Genestealer Patriarch's first ability triggers, putting an infection counter on a creature an opponent controls.
Cast Fate Transfer by paying its cost, moving the infection counter from the opponent's creature onto a creature you control.
Activate Blasting Station by tapping it and sacrificing the creature with an infection counter on it.
When the creature dies, Reluctant Role Model and Genestealer Patriarch's second ability trigger.
Resolve the Reluctant Role Model trigger, putting an infection counter onto another creature you control.
Resolve the Genestealer Patriarch trigger, causing you to create a token copy of the sacrificed creature that is a Tyranid in addition to its other types.
When the creature enters, Blasting Station triggers, untapping itself.
Resolve the Blasting Station ability from step 4, dealing 1 damage.
Repeat from step 4.

Infinite creature ETB

Infinite creature LTB

Infinite creature sacrifice triggers

Infinite damage

Infinite death triggers

Genestealer Patriarch

Blasting Station

Reluctant Role Model

Declare Genestealer Patriarch as an attacker.
Genestealer Patriarch's first ability triggers, putting an infection counter on a creature an opponent controls.
Cast Fate Transfer by paying {1}{U/B}, moving the infection counter from the opponent's creature onto another creature you control.
Activate Ashnod's Altar by sacrificing the creature with an infection counter on it, adding {C}{C}.
The creature dies, triggering Resourceful Defense and Genestealer Patriarch's second ability.
Resolve the Resourceful Defense trigger, putting an infection counter onto another creature you control.
Resolve the Genestealer Patriarch trigger, causing you to create a token copy of the sacrificed creature that is a Tyranid in addition to its other types.
Repeat from step 4.

Infinite colorless mana

Resourceful Defense

Ashnod's Altar

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