Cast Harmless Offering by paying {2}{R}, giving Nine Lives to an opponent.
Cast Austere Command by paying {4}{W}{W}, destroying all enchantments.
Nine Lives leaves the battlefield, causing its controller to lose the game.

Target opponent loses the game

Nine Lives

Harmless Offering

Austere Command

Activate Zedruu by paying {R}{W}{U}, giving target opponent control of Nine Lives.
Cast Austere Command by paying {4}{W}{W}, destroying all enchantments.
Nine Lives leaves the battlefield, causing its controller to lose the game.

Zedruu the Greathearted

Cast Donate by paying {2}{U}, giving Nine Lives to an opponent.
Cast Austere Command by paying {4}{W}{W}, destroying all enchantments.
Nine Lives leaves the battlefield, causing its controller to lose the game.

Donate

Cast Austere Command by paying its mana cost, destroying all creatures.
Cast Biorhythm by paying its mana cost, causing each player's life total to become equal to the number of creatures they control.
Each player that controls no creatures loses the game due to having 0 life.

Draw the game

Each opponent loses the game

Biorhythm

Cast Angel's Grace by paying {W}.
Cast Fractured Identity by paying {3}{W}{U}, exiling Nine Lives and causing each opponent to create a token copy of it.
Nine Lives leaves the battlefield, however you cannot lose the game due to Angel's Grace.
Cast Austere Command by paying its mana cost, destroying all enchantments.
When each opponent's Nine Lives leaves the battlefield, they each trigger, causing each opponent to lose the game.

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