Activate O'aka by tapping it and removing a counter from a nonland permanent, causing you to draw a card.
Teferi's Talent triggers, putting a counter on the planeswalker it is attached to.
Activate Mind Over Matter by discarding a card, untapping O'aka.
Repeat.

Infinite self-discard triggers

Infinite draw triggers

Infinite looting

O'aka, Traveling Merchant

Mind Over Matter

Teferi's Talent

Cast Gonti's Aether Heart by paying {6}.
When Gonti's Aether Heart enters the battlefield, it triggers, causing you to get {E}{E}.
Deal combat damage to an opponent using Piper. 
Piper triggers, creating at least three Clue tokens.
When the Clues enter the battlefield, Gonti's Aether Heart triggers that many times, causing you to get {E}{E} for each Clue.
Activate Gonti's Aether Heart by paying eight {E} and exiling it, causing you to take an extra turn after this one.
Activate Karn's second loyalty ability by removing two loyalty counters from it, putting Gonti's Aether Heart from exile into your hand. 
Activate a Clue by paying {2} and sacrificing it.
Piper triggers, putting a +1/+1 counter on a creature you control.
Resolve the Clue ability, causing you to draw a card.
Teferi's Talent triggers, putting a loyalty counter on Karn.
Move to your next turn.
During your draw step, you will draw a card. When you do, Teferi's Talent triggers, putting a loyalty counter on Karn.
Repeat.

Infinite turns

Karn, the Great Creator

Gonti's Aether Heart

Piper Wright, Publick Reporter

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