Activate Priest of Yawgmoth by tapping and sacrificing Spine of Ish Sah, adding seven {B}.
Spine of Ish Sah triggers, returning itself from your graveyard to your hand.
Cast Spine of Ish Sah by paying {7}.
Paradox Engine triggers, untapping all nonland permanents you control.
Spine of Ish Sah enters the battlefield, destroying target permanent.
Repeat.

Destroy any number of target permanent(s) opponents control

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