Activate Mairsil using Tree of Perdition's ability by tapping it, exchanging target opponent's life total with Mairsil's toughness.
Activate Mairsil using Spikeshot Elder's ability by paying ({1} magic symbol) ({R} magic symbol) ({R} magic symbol) , dealing damage equal to Mairsil's power to the opponent.
The opponent loses the game due to having zero or less life.