Activate Oreskos Sun Guide by tapping it, adding {U}.
Activate Pemmin's Aura by paying {U}, untapping Oreskos Sun Guide.
Oreskos Sun Guide triggers, causing you to gain 2 life.
Repeat.

Infinite lifegain triggers

Infinite lifegain

Oreskos Sun Guide

Pemmin's Aura

Paradise Mantle

Activate Oreskos Sun Guide using Seeker of Skybreak's ability by tapping it, untapping Oreskos Sun Guide
Oreskos Sun Guide triggers, causing you to gain 2 life.
Repeat.

Agatha's Soul Cauldron

Seeker of Skybreak

Activate Clock of Omens by tapping it and Oreskos Sun Guide, targeting Oreskos Sun Guide.
Ertha Jo triggers, copying Clock of Omens' ability, targeting Clock of Omens.
Resolve both Clock of Omens  abilities, untapping it and Oreskos Sun Guide.
Oreskos Sun Guide triggers, causing you to gain 2 life.
Repeat.

Ertha Jo, Frontier Mentor

Clock of Omens

Mycosynth Lattice

Activate Oreskos Sun Guide using Kiora's Follower's ability by tapping it, untapping another creature you control that has a +1/+1 counter on it.
Activate the other creature using Kiora's Follower's ability by tapping it, untapping Oreskos Sun Guide
Oreskos Sun Guide triggers, causing you to gain 2 life.
Repeat.

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