Activate Master Transmuter by paying {U}, tapping it and returning Breya from the battlefield to your hand, putting Breya onto the battlefield from your hand.
Breya enters the battlefield, creating two 1/1 Thopter artifact creature tokens.
Activate Clock of Omens by tapping the Thopters, untapping Master Transmuter.
Activate Phyrexian Altar by sacrificing a Thopter, adding {U}.
Repeat.
Once you have infinite creature tokens and infinite colored mana, you may activate Breya's ability infinite times.

Infinite colored mana

Infinite damage

Infinite death triggers

Infinite creature ETB

Infinite lifegain

Infinite lifegain triggers

Infinite creature LTB

Infinite creature sacrifice triggers

Infinite tapped creature tokens

Reduce the toughness of creatures opponents control to 0

Breya, Etherium Shaper

Master Transmuter

Phyrexian Altar

Clock of Omens

Activate Krark-Clan Ironworks by sacrificing Sword of the Meek, adding {C}{C}.
Sword of the Meek dies, triggering Slagstone Refinery, creating a tapped Powerstone token that enters the battlefield as a 1/1 creature due to March of the Machines and Master of Etherium.
Sword of the Meek triggers, returning itself from your graveyard to the battlefield, but not attaching itself to the Powerstone due to Sword of the Meek becoming a creature.
Repeat.

Infinite colorless mana

Infinite tapped Powerstone tokens

Slagstone Refinery

March of the Machines

Sword of the Meek

Krark-Clan Ironworks

Master of Etherium

Activate Ashnod's Altar by sacrificing Sword of the Meek, adding {C}{C}.
Sword of the Meek dies, triggering Slagstone Refinery, creating a tapped Powerstone token that enters the battlefield as a 1/1 creature due to March of the Machines and Master of Etherium.
Sword of the Meek triggers, returning itself from your graveyard to the battlefield, but not attaching itself to the Powerstone due to Sword of the Meek becoming a creature.
Repeat.

Ashnod's Altar

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