Persist Creature dies, its persist ability triggers, returning it from your graveyard to the battlefield with a -1/-1 counter on it and at least one +1/+1 counter on it due to
Bioengineered Future.
Remove a -1/-1 counter and a +1/+1 counter from that creature as a state-based action.
Resolve the
Altar of Dementia ability.
Repeat.
Results
Infinite creature ETB.
Infinite creature LTB.
Infinite death triggers.
Infinite mill.
Infinite creature sacrifice triggers.
Infinite self-mill.
Metadata
In 189 decks according to EDHREC.
Bracket Tag
This combo has been estimated to be Exhibition (Bracket 1+).