Activate Soul of New Phyrexia by paying {5}, giving all permanents you control indestructible until end of turn.
Deal combat damage to any opponent with the creature that has Worldslayer equipped, destroying all of your opponent' permanents.

Destroy all of your opponents' permanents on each of your turns

Worldslayer

Soul of New Phyrexia

Activate Soul of New Phyrexia's first ability by paying {5}, giving permanents you control indestructible until end of turn.
Activate Diaochan by tapping it, destroying an opponent's creature and any creature of that opponent's choice.
If the opponent chooses a creature you control to be destroyed, it is not destroyed due to it having indestructible.
The creature the opponent controls dies, triggering Diaochan, untapping Diaochan.
Repeat from step 2.

Combos with "Soul of New Phyrexia"