Cast Leshrac's Sigil by paying 4 life.
K'rrik and Aetherflux Reservoir triggers.
Resolve the K'rrik triggers, putting a +1/+1 counter on it.
Resolve the Aetherflux Reservoir triggers, gaining you life equal to the number of spells that you have cast this turn.
Activate Leshrac Sigil's second ability by paying 4 life, returning it to your hand.
Repeat for infinite life.
Once you have infinite life, you can activate Aetherflux Reservoir by paying 50 life, dealing 50 damage to any target.

Infinite damage

Infinite lifegain

Infinite lifegain triggers

Infinitely large K'rrik

Infinite storm count

Aetherflux Reservoir

Leshrac's Sigil

K'rrik, Son of Yawgmoth

Cast Leshrac's Sigil for 4 life.
When you cast Leshrac's Sigil, extort triggers for each creature go on the stack.
Pay 2 life for each netting you 1 life each time.
Return Leshrac's Sigil to your hand using its ability and paying 4 life.
Repeat.

Infinite lifeloss

Pontiff of Blight

Combos with "Leshrac's Sigil"