Cast Role Reversal by paying {U}{U}{R}, exchanging control of an enchantment an opponent controls and Nefarious Lich.
Activate Despotic Scepter by tapping it, destroying Nefarious Lich.
When Nefarious Lich leaves the battlefield, it triggers, causing its controller to lose the game.

Target opponent loses the game

Despotic Scepter

Nefarious Lich

Role Reversal

Cast Role Reversal targeting Vilis, Broker of Blood and a creature an opponent controls.
Once that opponent draws a card they draw their entire library and take damage equal to the amount of cards drawn.

Kill an opponent

Vilis, Broker of Blood

Underworld Dreams

Cast Role Reversal by paying {U}{U}{R}, exchanging control of an enchantment an opponent controls and Nefarious Lich.
Activate Staff of Compleation's first ability by tapping it and paying 1 life, destroying Nefarious Lich.
When Nefarious Lich leaves the battlefield, it triggers, causing its controller to lose the game.

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