Cast Selfless Squire by paying {3}{W}.
When Selfless Squire enters the battlefield, its first ability triggers, preventing all damage that would be dealt to you this turn.
Cast Wheel of Misfortune by paying {2}{R}, choosing an arbitrarily large number, and preventing the damage it would deal to you due to Selfless Squire.
Selfless Squire's second ability triggers, putting a number of +1/+1 counters on it equal to the damage prevented.

Infinite +1/+1 counters on Selfless Squire

Selfless Squire

Wheel of Misfortune

Cast Wheel of Misfortune by paying {2}{R}.
Holding priority, cast Intervention Pact by paying {0}, preventing all damage dealt by Wheel of Misfortune to you, and causing you to gain that much life.
Resolve Wheel of Misfortune, choosing an arbitrarily large number, and causing you to gain life equal to the number you chose.

Infinite lifegain

Intervention Pact

Cast Martyrdom by paying {1}{W}{W}, targeting Brash Taunter.
Cast Wheel of Misfortune by paying {2}{R}.
Holding priority, activate Brash Taunter's ability from Martyrdom any number of times by paying {0}, causing any amount of damage that would be dealt to you to be dealt to Brash Taunter instead this turn.
Resolve Wheel of Misfortune, choosing an arbitrarily large number and dealing an arbitrarily large amount of damage to the targeted creature and to Brash Taunter.
Brash Taunter triggers, targeting an opponent.
Holding priority, activate Brash Taunter's ability from Martyrdom many times by paying {0}, causing the next large amount of damage that would be dealt to the targeted opponent to be dealt to Brash Taunter instead this turn.
Resolve Brash Taunter's ability, redirecting some of the damage back to Brash Taunter but still dealing lethal damage to the opponent.
Repeat from step 5 once for each remaining opponent.

Infinite damage

Brash Taunter

Martyrdom

Cast Wheel of Misfortune by paying {2}{R}, choosing an arbitrarily large number, and causing you to gain life equal to the number you chose due to Purity.

Purity

Cast Wheel of Misfortune by paying {2}{R}.
Holding priority, cast Reverse Damage by paying {1}{W}{W}, preventing all damage dealt by Wheel of Misfortune to you, and causing you to gain that much life.
Resolve Wheel of Misfortune, choosing an arbitrarily large number, and causing you to gain life equal to the number you chose.

Reverse Damage

Cast Wheel of Misfortune by paying {2}{R}.
Holding priority, cast Hallow by paying {W}, preventing all damage dealt by Wheel of Misfortune to you, and causing you to gain that much life.
Resolve Wheel of Misfortune, choosing an arbitrarily large number, and causing you to gain life equal to the number you chose.

Hallow

Activate Mindslaver by paying {4}, tapping it, and sacrificing it, gaining control of them during their next turn.
Move to their turn.
Cast Wheel of Misfortune for {2}{R}, selecting an arbitrarily large number for the opponent you control.
Wheel of Misfortune resolves, dealing an amount of damage to that player equal to the number chosen.

Infinite damage to target opponent

Mindslaver

Vedalken Orrery

Cast Wheel of Misfortune by paying {2}{R}.
Holding priority, cast Samite Ministration by paying {1}{W}, preventing all damage dealt by Wheel of Misfortune to you, and causing you to gain that much life.
Resolve Wheel of Misfortune, choosing an arbitrarily large number, and causing you to gain life equal to the number you chose.

Samite Ministration

Cast Wheel of Misfortune by paying {2}{R}.
Holding priority, activate Cho-Arrim Alchemist by paying {1}{W}{W}, tapping it and discarding a card, preventing all damage dealt by Wheel of Misfortune to you, and causing you to gain that much life.
Resolve Wheel of Misfortune, choosing an arbitrarily large number, and causing you to gain life equal to the number you chose.

Cho-Arrim Alchemist

Leyline of Anticipation

Activate Teferi's +1 loyalty ability, allowing you to cast sorcery spells whenever you could cast an instant until your next turn.
Activate Mindslaver by paying {4}, tapping it, and sacrificing it, gaining control of them during their next turn.
Move to their turn.
Cast Wheel of Misfortune for {2}{R}, selecting an arbitrarily large number for the opponent you control.
Wheel of Misfortune resolves, dealing an amount of damage to that player equal to the number chosen.

Teferi, Time Raveler

Hypersonic Dragon

Activate Mindslaver by paying {4}, tapping and sacrificing it, causing you to gain control of target opponent during their next turn.
Move to the opponent's turn.
Cast Wheel of Misfortune by paying {2}{R}, selecting an arbitrarily large number for the opponent you control.
Wheel of Misfortune resolves, dealing that much damage to the opponent.
The opponent loses the game due to having zero or less life.

Najal, the Storm Runner

Cast Wheel of Misfortune by paying {2}{R}, choosing an arbitrarily large number.
Resolve Wheel of Fortune, dealing an arbitrarily large amount of damage to you, with your life total not changing due to Platinum Emperion.
Darien triggers, causing you to create a number of 1/1 Soldier creature tokens equal to the amount of damage dealt this way.

Infinite creature tokens

Infinite ETB

Darien, King of Kjeldor

Platinum Emperion

Cast Wheel of Misfortune by paying {2}{R}, choosing an arbitrarily large number.
Resolve Wheel of Fortune, dealing an arbitrarily large amount of damage to you, with you not losing the game due to Platinum Angel.
Darien triggers, causing you to create a number of 1/1 Soldier creature tokens equal to the amount of damage dealt this way.

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