Cast Repeated Reverberation by paying {2}{R}{R} and sacrificing a creature with power two or greater.
Repeated Reverberation's casualty ability triggers, creating two copies of it due to Twinning Staff.
Resolve each Repeated Reverberation, causing you to copy the next instant or sorcery spell you cast six times.
Cast Vraska's Fall by paying {2}{B}.
Each Repeated Reverberation triggers, copying Vraska's Fall a total of nine times due to Twinning Staff.
Resolve each Vraska's Fall, causing each opponent to get ten poison counters and sacrifice ten creatures and/or planeswalkers.
Each opponent loses the game due to having ten or more poison counters.

Each opponent loses the game

Anhelo, the Painter

Twinning Staff

Repeated Reverberation

Vraska's Fall

Cast Repeated Reverberation by paying {2}{R}{R} and sacrificing a creature with power two or greater.
Repeated Reverberation's casualty ability triggers, creating two copies of it due to Twinning Staff.
Resolve each Repeated Reverberation, causing you to copy the next instant or sorcery spell you cast six times.
Cast Prologue to Phyresis by paying {1}{U}.
Each Repeated Reverberation triggers, copying Prologue to Phyresis a total of nine times due to Twinning Staff.
Resolve each Prologue to Phyresis, causing each opponent to get ten poison counters, and you to draw ten cards.
Each opponent loses the game due to having ten or more poison counters.

Prologue to Phyresis

Cast Repeated Reverberation by paying {2}{R}{R} and sacrificing a creature with power two or greater.
Repeated Reverberation's casualty ability triggers, creating two copies of it due to Twinning Staff.
Resolve each Repeated Reverberation, causing you to copy the next instant or sorcery spell you cast six times.
Cast Infectious Inquiry by paying {2}{B}.
Each Repeated Reverberation triggers, copying Infectious Inquiry a total of nine times due to Twinning Staff.
Resolve each Infectious Inquiry, causing each opponent to get ten poison counters, and causing you to lose twenty life and draw twenty cards.
Each opponent loses the game due to having ten or more poison counters.

Infectious Inquiry

Activate all mana producing nonland permanents you control by tapping them, adding at least {2}{U}.
Cast Repeated Reverberation by paying {2}{R}{R}, causing you to create two copies of the next instant spell you cast this turn.
Cast Dramatic Reversal by paying {1}{U}.
Repeated Reverberation triggers, creating two copies of Dramatic Reversal.
Resolve a copy of Dramatic Reversal, untapping all nonland permanents you control.
Activate all mana producing nonland permanents you control by tapping them, adding at least {2}{U}.
Activate Errant by paying {1}{U} and tapping it, creating a copy of the Dramatic Reversal copy.
Repeat from step 5.

Infinite magecraft triggers

Infinite mana nonland permanents you control can produce

Infinite untap of nonland permanents you control

Errant, Street Artist

Dramatic Reversal

Cast Repeated Reverberation by paying {2}{R}{R} and sacrificing a creature with power two or greater.
Repeated Reverberation's casualty ability triggers, creating two copies of it due to Twinning Staff.
Resolve each Repeated Reverberation, causing you to copy the next instant or sorcery spell you cast six times.
Cast Phyresis Outbreak by paying {2}{B}.
Each Repeated Reverberation triggers, copying Phyresis Outbreak a total of nine times due to Twinning Staff.
Resolve each Phyresis Outbreak, causing each opponent to get ten poison counters.
Each opponent loses the game due to having ten or more poison counters.

Phyresis Outbreak

Cast Repeated Reverberation by paying {2}{R}{R}, copying the next instant or sorcery spell you cast twice.
Cast Biovisionary by paying {1}{G}{U}.
Holding priority, cast Double Major by paying {G}{U}, targeting Biovisionary.
Repeated Reverberation triggers, copying Double Major twice, with both copies targeting Biovisionary.
Resolve all Double Majors, creating three copies of the Biovisionary spells.
Resolve all Biovisionary spells, causing you to have a nontoken Biovisionary and three token Biovisionaries.
At the beginning of your end step, each Biovisionary triggers.
Resolve the first trigger, causing you to win the game.

Win the game

Biovisionary

Double Major

Cast Repeated Reverberation by paying {2}{R}{R}, copying the next instant or sorcery spell you cast twice.
Cast Quasiduplicate by paying {1}{U}{U}, targeting Biovisionary.
Repeated Reverberation triggers, copying Quasiduplicate twice, with both copies targeting Biovisionary.
Resolve all Quasiduplicates, creating three token copies of Biovisionary.
At the beginning of your end step, each Biovisionary triggers.
Resolve the first trigger, causing you to win the game.

Quasiduplicate

Cast Repeated Reverberation by paying {2}{R}{R}, copying the next instant or sorcery spell you cast twice.
Cast Cackling Counterpart by paying {1}{U}{U}, targeting Biovisionary.
Repeated Reverberation triggers, copying Cackling Counterpart twice, with both copies targeting Biovisionary.
Resolve all Cackling Counterparts, creating three token copies of Biovisionary.
At the beginning of your end step, each Biovisionary triggers.
Resolve the first trigger, causing you to win the game.

Cackling Counterpart

Cast Repeated Reverberation by paying {2}{R}{R}, copying the next instant or sorcery spell you cast twice.
Cast Croaking Counterpart by paying {1}{G}{U}, targeting Biovisionary.
Repeated Reverberation triggers, copying Croaking Counterpart twice, with both copies targeting Biovisionary.
Resolve all Croaking Counterparts, creating three token copies of Biovisionary that are 1/1 Frogs.
At the beginning of your end step, each Biovisionary triggers.
Resolve the first trigger, causing you to win the game.

Combos with "Repeated Reverberation"