- Bloodchief Ascension and Mindcrank on the battlefield.
- Three or more quest counters on Bloodchief Ascension.
- You have a way to make an opponent lose life.
- Cause one or more opponents to lose life.
- Mindcrank triggers once for each life loss event, causing that player to mill cards equal to the amount of life lost.
- Bloodchief Ascension triggers once for each card milled, causing that player to lose 2 life and you to gain 2 life for each trigger.
- Repeat from step 2.
- Near-infinite lifeloss.
- Near-infinite lifegain triggers.
- Near-infinite lifegain.
- Infinite mill.